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Disorders of other endocrine glands

DOID EFO MESH SNOMED PheWeb

E4_ENDOGLAND

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E20-E35
Cause of death: ICD-10 E20-E35

2 out of 7 registries used, show all original rules.

12022

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Check minimum number of events None

12022

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Include endpoints

15893

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Remove individuals based on genotype QC

15289

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E4_ENDOGLAND

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 15289 10289 5000
Unadjusted prevalence (%) 4.05 4.88 3.01
Mean age at first event (years) 48.93 47.39 52.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.01 [1.52, 2.65] 1.1e-6 1873
15 years 0.01 1.36 [1.10, 1.68] 4.9e-3 840
5 years 0.00 2.59 [2.20, 3.05] 2.8e-30 533
1 year 0.00 5.73 [4.74, 6.93] 1.2e-72 230

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDOGLAND – Disorders of other endocrine glands
GWS hits: 4

Survival analyses between endpoints

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Plot

before Disorders of other endocrine glands
after Disorders of other endocrine glands

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of other endocrine glands

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Endpoint not on priority list, no data to show.