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Other endocrine disorders

DOID EFO MESH SNOMED PheWeb

E4_ENDODIS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E34, E35
Cause of death: ICD-10 E34, E35

2 out of 7 registries used, show all original rules.

1559

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Check minimum number of events None

1559

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Include endpoints

1653

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Remove individuals based on genotype QC

1576

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E4_ENDODIS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other endocrine disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1576 935 641
Unadjusted prevalence (%) 0.42 0.44 0.39
Mean age at first event (years) 29.96 28.94 31.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.73 [1.08, 6.88] 3.4e-2 91
15 years 0.01 2.06 [1.00, 4.22] 4.8e-2 40
5 years 0.01 4.92 [2.77, 8.76] 5.9e-8 28
1 year 0.00 10.50 [5.32, 20.75] 1.3e-11 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODIS – Other endocrine disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other endocrine disorders
after Other endocrine disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other endocrine disorders

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Endpoint not on priority list, no data to show.