≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Ovarian dysfunction

DOID EFO MESH SNOMED PheWeb

E4_OVARDYS

ovarian dysfunction: The inability of the ovaries to function.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

219462

diagram downward connector

Check conditions None

219462

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28
Cause of death: ICD-10 E28

2 out of 7 registries used, show all original rules.

1720

diagram downward connector

Check minimum number of events None

1720

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

2127

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2010

diagram downward connector
E4_OVARDYS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio ovarialis

Similar endpoints

↥

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2010 2010 -
Unadjusted prevalence (%) 0.53 0.95 -
Mean age at first event (years) 30.54 30.54 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.40 [1.10, 5.22] 2.8e-2 35
15 years 0.01 1.58 [0.68, 3.68] 2.9e-1 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 6

Survival analyses between endpoints

↥

Plot

before Ovarian dysfunction
after Ovarian dysfunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ovarian dysfunction

↥

Endpoint not on priority list, no data to show.