Ovarian dysfunction


ovarian dysfunction: The inability of the ovaries to function.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28
Cause of death: ICD-10 E28

2 out of 7 registries used, show all original rules.


diagram downward connector

Check minimum number of events None


diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC


diagram downward connector

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio ovarialis

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 2010 2010 -
Unadjusted prevalence (%) 0.53 0.95 -
Mean age at first event (years) 30.54 30.54 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.40 [1.10, 5.22] 2.8e-2 35
15 years 0.01 1.58 [0.68, 3.68] 2.9e-1 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 6

Survival analyses between endpoints


before Ovarian dysfunction
after Ovarian dysfunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ovarian dysfunction

Endpoint not on priority list, no data to show.