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Diabetic retinopathy

DM_RETINOPATHY

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

DIABETES_FG

71098

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

10413

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DM_RETINOPATHY

Control definitions

Control exclude DM_SEVERAL_COMPLICATIONS

Extra metadata

First used in FinnGen datafreeze DF8

Similar endpoints

List of similar endpoints to Diabetic retinopathy based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 10413 4568 5845
Unadjusted prevalence (%) 2.76 2.17 3.52
Mean age at first event (years) 57.02 55.95 57.86

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: DM_RETINOPATHY – Diabetic retinopathy
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Diabetic retinopathy

Endpoint not on priority list, no data to show.