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Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)

DOID EFO MESH SNOMED PheWeb

DM_VITREOUS_BLEEDING

neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H43.1
Cause of death: ICD-10 H43.1

2 out of 7 registries used, show all original rules.

2914

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Check minimum number of events None

2914

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Include endpoints None

2914

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Remove individuals based on genotype QC

2820

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DM_VITREOUS_BLEEDING

Control definitions

Control exclude DM_RETINOPATHY

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 H43
Name in latin Haemorrhagia corporis vitrei

Summary Statistics

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Key figures

All Female Male
Number of individuals 2820 1337 1483
Unadjusted prevalence (%) 0.75 0.63 0.89
Mean age at first event (years) 58.35 57.53 59.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.83 [1.80, 4.47] 7.2e-6 403
15 years 0.01 1.85 [1.29, 2.66] 8.9e-4 194
5 years 0.00 3.24 [2.22, 4.72] 1.0e-9 135
1 year 0.00 4.17 [2.63, 6.62] 1.4e-9 35

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_VITREOUS_BLEEDING – Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)
GWS hits: 1

Survival analyses between endpoints

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Plot

before Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)
after Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)

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Endpoint not on priority list, no data to show.