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Neovascular glaucoma

DOID EFO MESH SNOMED PheWeb

DM_NEOVASCULAR_GLAUCOMA

neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.5
Cause of death: ICD-10 H40.5

2 out of 7 registries used, show all original rules.

1151

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Check minimum number of events None

1151

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Include endpoints None

1151

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Remove individuals based on genotype QC

1100

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DM_NEOVASCULAR_GLAUCOMA

Control definitions

Control exclude DM_RETINOPATHY

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Summary Statistics

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Key figures

All Female Male
Number of individuals 1100 510 590
Unadjusted prevalence (%) 0.29 0.24 0.35
Mean age at first event (years) 60.36 56.94 63.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.00 [2.45, 6.53] 2.9e-8 239
15 years 0.01 1.91 [1.31, 2.79] 7.8e-4 96
5 years 0.01 4.34 [3.27, 5.75] 3.0e-24 102
1 year 0.00 4.63 [2.86, 7.48] 3.9e-10 26

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_NEOVASCULAR_GLAUCOMA – Neovascular glaucoma
GWS hits: 1

Survival analyses between endpoints

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Plot

before Neovascular glaucoma
after Neovascular glaucoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Neovascular glaucoma

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Endpoint not on priority list, no data to show.