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Unspecified diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

DM_RETINA_NOS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

DM_EYE_OPER

6886

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H3609|E1.7|E1.3
Hospital discharge: ICD-9 3620A|2504
Hospital discharge: ICD-8 25002
Hospital discharge: excluded ICD-10 E12.3+
Cause of death: ICD-10 H3609|E1.7|E1.3
Cause of death: ICD-9 3620A|2504
Cause of death: ICD-8 25002
Cause of death: excluded ICD-10 E12.3+

2 out of 7 registries used, show all original rules.

3594

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Check minimum number of events None

3594

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Include endpoints None

3594

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Remove individuals based on genotype QC

3494

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DM_RETINA_NOS

Control definitions

Control exclude DM_RETINOPATHY
Control conditions not DM_EYE_OPER

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3494 1411 2083
Unadjusted prevalence (%) 0.93 0.67 1.25
Mean age at first event (years) 49.08 47.02 50.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.38 [2.36, 4.83] 2.3e-11 569
15 years 0.02 2.36 [1.75, 3.18] 1.9e-8 275
5 years 0.00 3.18 [2.39, 4.23] 1.9e-15 111
1 year 0.00 7.22 [5.08, 10.28] 4.7e-28 47

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_RETINA_NOS – Unspecified diabetic retinopathy
GWS hits: 6

Survival analyses between endpoints

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Plot

before Unspecified diabetic retinopathy
after Unspecified diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetic retinopathy

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Endpoint not on priority list, no data to show.