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Polyarthropathies

DOID EFO MESH PheWeb

M13_POLYARTHROPATHIES

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05-M14
Cause of death: ICD-10 M05-M14

2 out of 7 registries used, show all original rules.

30194

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Check minimum number of events None

30194

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Include endpoints

33183

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Remove individuals based on genotype QC

32199

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M13_POLYARTHROPATHIES

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 32199 17281 14918
Unadjusted prevalence (%) 8.54 8.20 8.97
Mean age at first event (years) 53.07 49.46 57.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.30 [1.96, 2.70] 5.9e-24 4396
15 years 0.01 1.50 [1.32, 1.69] 1.7e-10 1832
5 years 0.00 2.89 [2.61, 3.19] 1.2e-94 1243
1 year 0.00 6.30 [5.53, 7.18] <1e-100 550

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYARTHROPATHIES – Polyarthropathies
GWS hits: 14

Survival analyses between endpoints

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Plot

before Polyarthropathies
after Polyarthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polyarthropathies

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Endpoint not on priority list, no data to show.