Gout

DOID EFO MESH SNOMED PheWeb

M13_GOUT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M10

Hospital discharge: ICD-9 2740

Hospital discharge: ICD-8 2740

Cause of death: ICD-10 M10

Cause of death: ICD-9 2740

Cause of death: ICD-8 2740

KELA reimbursements: KELA codes 212

3 out of 7 registries used, show all original rules.

8793

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Check minimum number of events None

8793

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Include endpoints None

8793

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Remove individuals based on genotype QC

8489

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M13_GOUT

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M05-M14

NAME	M13_GOUT
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M10
HD_ICD_9	2740
HD_ICD_8	2740
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M10
COD_ICD_9	2740
COD_ICD_8	2740
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB	212
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Gout based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8489	1943	6546
Unadjusted prevalence (%)	2.25	0.92	3.94
Mean age at first event (years)	64.76	66.83	64.15

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.22 [2.59, 4.02]	2.5e-25	2159
15 years	0.01	1.57 [1.32, 1.88]	6.6e-7	760
5 years	0.00	3.75 [3.18, 4.42]	8.9e-56	765
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_GOUT – Gout
GWS hits: 14

Survival analyses between endpoints

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Plot

before Gout
after Gout

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Table

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Drugs most likely to be purchased after Gout

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Endpoint not on priority list, no data to show.