Juvenile rheuma

DOID EFO MESH PheWeb

M13_JUVERHEU

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M08.0

Hospital discharge: ICD-9 7143A

Hospital discharge: ICD-8 7120

Cause of death: ICD-10 M08.0

Cause of death: ICD-9 7143A

Cause of death: ICD-8 7120

2 out of 7 registries used, show all original rules.

704

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Check minimum number of events None

704

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Include endpoints None

704

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Remove individuals based on genotype QC

692

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M13_JUVERHEU

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M08

Name in latin Arthritis rheumatoides juvenilis

NAME	M13_JUVERHEU
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M080
HD_ICD_9	7143A
HD_ICD_8	7120
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M080
COD_ICD_9	7143A
COD_ICD_8	7120
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Juvenile rheuma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	692	539	153
Unadjusted prevalence (%)	0.18	0.26	0.09
Mean age at first event (years)	20.98	21.05	20.73

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.30 [0.37, 4.58]	6.8e-1	20
15 years	0.01	0.86 [0.21, 3.57]	8.3e-1	10
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_JUVERHEU – Juvenile rheuma
GWS hits: 1

Survival analyses between endpoints

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Plot

before Juvenile rheuma
after Juvenile rheuma

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Table

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Drugs most likely to be purchased after Juvenile rheuma

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Endpoint not on priority list, no data to show.