Psoriatic arthropathies

DOID EFO MESH SNOMED PheWeb

M13_PSORIARTH

psoriatic arthritis: Joint inflammation associated with psoriasis.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M07.0*, M07.0*L40.5, M07.1*, M07.1*L40.5, M07.2*, M07.2*L40.5, M07.3*, M07.3*L40.5

Hospital discharge: ICD-9 6960

Hospital discharge: ICD-8 6960

Cause of death: ICD-10 M07.0*, M07.0*L40.5, M07.1*, M07.1*L40.5, M07.2*, M07.2*L40.5, M07.3*, M07.3*L40.5

Cause of death: ICD-9 6960

Cause of death: ICD-8 6960

2 out of 7 registries used, show all original rules.

3294

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Check minimum number of events None

3294

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Include endpoints None

3294

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Remove individuals based on genotype QC

3186

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M13_PSORIARTH

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

NAME	M13_PSORIARTH
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M07[0-3]
HD_ICD_9	6960
HD_ICD_8	6960
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M07[0-3]
COD_ICD_9	6960
COD_ICD_8	6960
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Psoriatic arthropathies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Other psoriatic arthropathies

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3186	1724	1462
Unadjusted prevalence (%)	0.84	0.82	0.88
Mean age at first event (years)	50.41	50.09	50.78

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.07 [1.37, 3.13]	5.4e-4	199
15 years	0.01	1.70 [1.22, 2.36]	1.8e-3	111
5 years	0.00	1.71 [1.14, 2.56]	9.9e-3	34
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_PSORIARTH – Psoriatic arthropathies
GWS hits: 10

Survival analyses between endpoints

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Plot

before Psoriatic arthropathies
after Psoriatic arthropathies

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Table

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Drugs most likely to be purchased after Psoriatic arthropathies

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