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Nerve, nerve root and plexus disorders

DOID EFO MESH SNOMED PheWeb

G6_NERPLEX

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G50-G59, G53.0*B02.20, G53.0*B02.21
Cause of death: ICD-10 G50-G59, G53.0*B02.20, G53.0*B02.21

2 out of 7 registries used, show all original rules.

42529

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Check minimum number of events None

42529

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Include endpoints

48404

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Remove individuals based on genotype QC

46900

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G6_NERPLEX

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 46900 28934 17966
Unadjusted prevalence (%) 12.44 13.73 10.80
Mean age at first event (years) 52.14 50.69 54.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.69 [1.50, 1.91] 1.7e-17 4031
15 years 0.01 1.18 [1.07, 1.31] 1.7e-3 1878
5 years 0.00 1.86 [1.67, 2.07] 1.5e-30 888
1 year 0.00 3.46 [2.98, 4.01] 2.2e-59 305

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NERPLEX – Nerve, nerve root and plexus disorders
GWS hits: 6

Survival analyses between endpoints

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Plot

before Nerve, nerve root and plexus disorders
after Nerve, nerve root and plexus disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nerve, nerve root and plexus disorders

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Endpoint not on priority list, no data to show.