Other and unspecified mononeuropathies of upper limb

G6_MONONPOTHUS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G56.8, G56.9
Hospital discharge: ICD-9 354[8-9]
Cause of death: ICD-10 G56.8, G56.9
Cause of death: ICD-9 354[8-9]

2 out of 7 registries used, show all original rules.

826

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Check minimum number of events None

826

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Include endpoints None

826

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Remove individuals based on genotype QC

798

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G6_MONONPOTHUS

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 798 449 349
Unadjusted prevalence (%) 0.21 0.21 0.21
Mean age at first event (years) 47.55 45.96 49.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.83 [0.97, 3.46] 6.2e-2 56
15 years 0.01 1.22 [0.63, 2.34] 5.5e-1 27
5 years 0.00 2.05 [0.99, 4.26] 5.3e-2 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MONONPOTHUS – Other and unspecified mononeuropathies of upper limb
GWS hits:

Survival analyses between endpoints

Plot

before Other and unspecified mononeuropathies of upper limb
after Other and unspecified mononeuropathies of upper limb

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified mononeuropathies of upper limb

Endpoint not on priority list, no data to show.