Brachial plexus disorders

G6_BRACHPLE

brachial plexus neuropathy: Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G54.0
Hospital discharge: ICD-9 3530
Cause of death: ICD-10 G54.0
Cause of death: ICD-9 3530

2 out of 7 registries used, show all original rules.

2840

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Check minimum number of events None

2840

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Include endpoints None

2840

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Remove individuals based on genotype QC

2757

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G6_BRACHPLE

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G54
Name in latin Morbositates plexus brachialis

Summary Statistics

Key figures

All Female Male
Number of individuals 2757 1993 764
Unadjusted prevalence (%) 0.73 0.95 0.46
Mean age at first event (years) 45.02 43.68 48.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.91 [1.08, 3.38] 2.7e-2 79
15 years 0.01 1.49 [0.86, 2.57] 1.6e-1 37
5 years 0.00 2.99 [1.68, 5.32] 1.9e-4 19
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_BRACHPLE – Brachial plexus disorders
GWS hits:

Survival analyses between endpoints

Plot

before Brachial plexus disorders
after Brachial plexus disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Brachial plexus disorders

Endpoint not on priority list, no data to show.