Carpal tunnel syndrome


carpal tunnel syndrome: Entrapment of the median nerve in the wrist that is characterized by numbness, tingling and painful movement.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G56.0
Hospital discharge: ICD-9 3540
Cause of death: ICD-10 G56.0
Cause of death: ICD-9 3540

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G56
Name in latin Syndroma canalis carpi

Summary Statistics

Key figures

All Female Male
Number of individuals 22426 15432 6994
Unadjusted prevalence (%) 5.95 7.32 4.21
Mean age at first event (years) 53.77 52.56 56.45


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.27 [1.05, 1.54] 1.4e-2 1266
15 years 0.01 0.91 [0.74, 1.11] 3.4e-1 648
5 years 0.00 1.19 [0.98, 1.45] 7.7e-2 249
1 year 0.00 1.24 [0.90, 1.73] 1.9e-1 47

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_CARPTU – Carpal tunnel syndrome
GWS hits: 40

Survival analyses between endpoints


before Carpal tunnel syndrome
after Carpal tunnel syndrome

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Drugs most likely to be purchased after Carpal tunnel syndrome

Endpoint not on priority list, no data to show.