Atypical facial pain


facial neuralgia: Neuralgic syndromes which feature chronic or recurrent facial pain as the primary manifestation of disease. Disorders of the trigeminal and facial nerves are frequently associated with these conditions.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G50.1
Hospital discharge: ICD-9 3502
Cause of death: ICD-10 G50.1
Cause of death: ICD-9 3502

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G50
Name in latin Dolor facialis atypicus

Summary Statistics

Key figures

All Female Male
Number of individuals 1372 1071 301
Unadjusted prevalence (%) 0.36 0.51 0.18
Mean age at first event (years) 53.60 52.43 57.75


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.18 [1.63, 6.18] 6.5e-4 53
15 years 0.01 1.84 [0.89, 3.83] 1.0e-1 27
5 years 0.00 2.60 [1.29, 5.26] 7.9e-3 13
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_ATYFAC – Atypical facial pain
GWS hits:

Survival analyses between endpoints


before Atypical facial pain
after Atypical facial pain

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Drugs most likely to be purchased after Atypical facial pain

Endpoint not on priority list, no data to show.