Substance use, excluding alcohol

DOID MESH PheWeb

F5_SUBSNOALCO

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

F5_OPIOIDS

F5_CANNABIS

F5_SEDAHYP

F5_COCAINE

F5_STIMUL

F5_HALLUCIN

F5_TOBAC

F5_SOLVENT

F5_OTHERSUB

6935

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Remove individuals based on genotype QC

6605

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F5_SUBSNOALCO

Control definitions

Control exclude F5_SUBSTANCE

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

NAME	F5_SUBSNOALCO
CONTROL_EXCLUDE	F5_SUBSTANCE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	F5_OPIOIDS\|F5_CANNABIS\|F5_SEDAHYP\|F5_COCAINE\|F5_STIMUL\|F5_HALLUCIN\|F5_TOBAC\|F5_SOLVENT\|F5_OTHERSUB
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Substance use, excluding alcohol based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6605	3077	3528
Unadjusted prevalence (%)	1.75	1.46	2.12
Mean age at first event (years)	41.73	41.74	41.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.11	7.44 [5.09, 10.86]	3.2e-25	700
15 years	0.02	3.41 [2.38, 4.89]	2.3e-11	249
5 years	0.01	8.35 [6.12, 11.40]	9.9e-41	230
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_SUBSNOALCO – Substance use, excluding alcohol
GWS hits: 1

Survival analyses between endpoints

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Plot

before Substance use, excluding alcohol
after Substance use, excluding alcohol

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Table

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Drugs most likely to be purchased after Substance use, excluding alcohol

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Endpoint not on priority list, no data to show.