Any mental disorder

KRA_PSY_ANYMENTAL

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]

Hospital discharge: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A

Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]

Cause of death: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A

Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

2 out of 7 registries used, show all original rules.

102919

Check minimum number of events None

102919

Include endpoints

KRA_PSY_DEMENTIA

VWXY20_SUICI_OTHER_INTENTI_SELF_H

103882

Remove individuals based on genotype QC

99751

KRA_PSY_ANYMENTAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF9

NAME	KRA_PSY_ANYMENTAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	KRA_PSY_DEMENTIA\|VWXY20_SUICI_OTHER_INTENTI_SELF_H
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F0[0-3]\|F051\|G30\|F[1-9]
HD_ICD_9	29[0-2]\|2941A\|29[5-9]\|30\|31[2-9]\|3310A\|3311A\|4378A
HD_ICD_8	29[0-1]\|29440\|29[5-9]\|30[0-1]\|3021\|30[3-8]\|310
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F0[0-3]\|F051\|G30\|F[1-9]
COD_ICD_9	29[0-2]\|2941A\|29[5-9]\|30\|31[2-9]\|3310A\|3311A\|4378A
COD_ICD_8	29[0-1]\|29440\|29[5-9]\|30[0-1]\|3021\|30[3-8]\|310
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Any mental disorder based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	99751	56932	42819
Unadjusted prevalence (%)	26.45	27.01	25.75
Mean age at first event (years)	43.90	41.36	47.28

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.29 [3.93, 4.69]	<1e-100	14872
15 years	0.01	2.28 [2.08, 2.51]	1.4e-65	4821
5 years	0.01	5.15 [4.79, 5.55]	<1e-100	4633
1 year	0.00	15.82 [14.38, 17.40]	<1e-100	3421

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder
GWS hits: 23

Survival analyses between endpoints

↥

Plot

before Any mental disorder
after Any mental disorder

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Any mental disorder

↥

≡ Risteys

R9

R8

R7

R6

R5

R4

R3