Any mental disorder


vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]
Hospital discharge: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A
Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310
Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]
Cause of death: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A
Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

2 out of 7 registries used, show all original rules.


diagram downward connector

Check minimum number of events None


diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC


diagram downward connector

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF9

Summary Statistics

Key figures

All Female Male
Number of individuals 99751 56932 42819
Unadjusted prevalence (%) 26.45 27.01 25.75
Mean age at first event (years) 43.90 41.36 47.28


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.29 [3.93, 4.69] <1e-100 14872
15 years 0.01 2.28 [2.08, 2.51] 1.4e-65 4821
5 years 0.01 5.15 [4.79, 5.55] <1e-100 4633
1 year 0.00 15.82 [14.38, 17.40] <1e-100 3421

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder
GWS hits: 23

Survival analyses between endpoints


before Any mental disorder
after Any mental disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Any mental disorder