≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Mental and behavioural disorders due to opioids

DOID EFO MESH SNOMED PheWeb

F5_OPIOIDS

opioid dependence: Disorders related or resulting from abuse or mis-use of opioids.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F11
Hospital discharge: ICD-9 3040|3055
Hospital discharge: ICD-8 304[0-1]
Cause of death: ICD-10 F11
Cause of death: ICD-9 3040|3055
Cause of death: ICD-8 304[0-1]

2 out of 7 registries used, show all original rules.

1176

diagram downward connector

Check minimum number of events None

1176

diagram downward connector

Include endpoints None

1176

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1108

diagram downward connector
F5_OPIOIDS

Control definitions

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu opioidum

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1108 494 614
Unadjusted prevalence (%) 0.29 0.23 0.37
Mean age at first event (years) 35.70 35.97 35.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 15.83 [9.70, 25.83] 2.1e-28 77
15 years 0.05 7.78 [4.61, 13.15] 1.6e-14 32
5 years 0.01 10.69 [5.76, 19.86] 6.4e-14 21
1 year 0.01 32.69 [15.49, 68.98] 5.7e-20 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: F5_OPIOIDS – Mental and behavioural disorders due to opioids
GWS hits:

Survival analyses between endpoints

↥

Plot

before Mental and behavioural disorders due to opioids
after Mental and behavioural disorders due to opioids

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mental and behavioural disorders due to opioids

↥

Endpoint not on priority list, no data to show.