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Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

DOID MESH PheWeb

F5_OTHERSUB

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F19
Hospital discharge: ICD-9 3059|3049
Hospital discharge: ICD-8 304[8-9]
Cause of death: ICD-10 F19
Cause of death: ICD-9 3059|3049
Cause of death: ICD-8 304[8-9]

2 out of 7 registries used, show all original rules.

2438

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Check minimum number of events None

2438

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Include endpoints None

2438

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Remove individuals based on genotype QC

2299

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F5_OTHERSUB

Control definitions

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu medicamentorum multorum et aliarum substantiarum psychotropicarum

Summary Statistics

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Key figures

All Female Male
Number of individuals 2299 902 1397
Unadjusted prevalence (%) 0.61 0.43 0.84
Mean age at first event (years) 31.76 31.82 31.72

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 10.18 [6.60, 15.68] 7.0e-26 198
15 years 0.03 5.69 [3.84, 8.42] 3.7e-18 65
5 years 0.01 11.24 [7.24, 17.45] 4.0e-27 44
1 year 0.01 72.06 [46.92, 110.68] 4.9e-85 55

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_OTHERSUB – Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances
GWS hits:

Survival analyses between endpoints

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Plot

before Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances
after Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

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Drugs most likely to be purchased after Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

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Endpoint not on priority list, no data to show.