Mental and behavioural disorders due to cannabinoids

DOID EFO MESH SNOMED PheWeb

F5_CANNABIS

cannabis dependence: Physical and psychological dependence on the drug cannabis.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F12

Hospital discharge: ICD-9 3052|3043

Hospital discharge: ICD-8 3045

Cause of death: ICD-10 F12

Cause of death: ICD-9 3052|3043

Cause of death: ICD-8 3045

2 out of 7 registries used, show all original rules.

1018

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Check minimum number of events None

1018

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Include endpoints None

1018

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Remove individuals based on genotype QC

939

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F5_CANNABIS

Control definitions

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F10-F19

Name in latin Perturbationes mentis et modi se gerendi ex usu cannabinoidum

NAME	F5_CANNABIS
CONTROL_EXCLUDE	F5_SUBSNOALCO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F12
HD_ICD_9	3052\|3043
HD_ICD_8	3045
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F12
COD_ICD_9	3052\|3043
COD_ICD_8	3045
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Mental and behavioural disorders due to cannabinoids based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	939	286	653
Unadjusted prevalence (%)	0.25	0.14	0.39
Mean age at first event (years)	27.57	27.16	27.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.19	13.82 [5.51, 34.66]	2.2e-8	49
15 years	0.05	8.38 [3.24, 21.67]	1.2e-5	17
5 years	0.04	31.01 [13.67, 70.37]	2.1e-16	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_CANNABIS – Mental and behavioural disorders due to cannabinoids
GWS hits: 1

Survival analyses between endpoints

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Plot

before Mental and behavioural disorders due to cannabinoids
after Mental and behavioural disorders due to cannabinoids

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Table

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Drugs most likely to be purchased after Mental and behavioural disorders due to cannabinoids

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Endpoint not on priority list, no data to show.