Substance abuse (more control exclusions)

PheWeb

KRA_PSY_SUBSTANCE_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

Apply sex-specific rule None

Check conditions None

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10-F19

Hospital discharge: ICD-9 29[1-2]|30[3-5]

Hospital discharge: ICD-8 291|30[3-4]

Hospital discharge: excluded ICD-10 F10.0

Hospital discharge: excluded ICD-9 3050A

Cause of death: ICD-10 F10-F19

Cause of death: ICD-9 29[1-2]|30[3-5]

Cause of death: ICD-8 291|30[3-4]

2 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints

KRA_PSY_ALCOH

Remove individuals based on genotype QC

23194

KRA_PSY_SUBSTANCE_EXMORE

Control definitions

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

NAME	KRA_PSY_SUBSTANCE_EXMORE
CONTROL_EXCLUDE	KRA_PSY_ANYMENTAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	KRA_PSY_ALCOH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F1
HD_ICD_9	29[1-2]\|30[3-5]
HD_ICD_8	291\|30[3-4]
HD_ICD_10_EXCL	F100
HD_ICD_9_EXCL	3050A
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F1
COD_ICD_9	29[1-2]\|30[3-5]
COD_ICD_8	291\|30[3-4]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Substance abuse (more control exclusions) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	23194	8232	14962
Unadjusted prevalence (%)	6.15	3.91	9.00
Mean age at first event (years)	45.20	41.41	47.29

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	4.79 [4.00, 5.73]	7.7e-66	4316
15 years	0.02	2.88 [2.52, 3.30]	4.0e-53	1662
5 years	0.00	5.09 [4.57, 5.66]	<1e-100	983
1 year	0.00	23.82 [21.14, 26.85]	<1e-100	939

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_SUBSTANCE_EXMORE – Substance abuse (more control exclusions)
GWS hits: 12

Survival analyses between endpoints

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Plot

before Substance abuse (more control exclusions)
after Substance abuse (more control exclusions)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Substance abuse (more control exclusions)

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3