Nontoxic goitre/thyroid nodule


No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

List of similar endpoints to Nontoxic goitre/thyroid nodule based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 9485 7899 1586
Unadjusted prevalence (%) 2.52 3.75 0.95
Mean age at first event (years) 51.85 50.58 58.19


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.18 [0.90, 1.55] 2.4e-1 736
15 years 0.01 0.91 [0.73, 1.15] 4.4e-1 316
5 years 0.00 1.64 [1.31, 2.05] 1.8e-5 146
1 year 0.00 2.18 [1.51, 3.14] 2.7e-5 36

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_NONTOXIC_THYROID – Nontoxic goitre/thyroid nodule
GWS hits: 53

Survival analyses between endpoints


before Nontoxic goitre/thyroid nodule
after Nontoxic goitre/thyroid nodule

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Drugs most likely to be purchased after Nontoxic goitre/thyroid nodule

Endpoint not on priority list, no data to show.