Nontoxic single thyroid nodule

E4_GOITRENOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.1
Hospital discharge: ICD-9 2410|2462
Cause of death: ICD-10 E04.1
Cause of death: ICD-9 2410|2462

2 out of 7 registries used, show all original rules.

2107

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Check minimum number of events None

2107

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Include endpoints None

2107

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Remove individuals based on genotype QC

2027

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E4_GOITRENOD

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica uninodularis

Summary Statistics

Key figures

All Female Male
Number of individuals 2027 1638 389
Unadjusted prevalence (%) 0.54 0.78 0.23
Mean age at first event (years) 50.98 49.34 57.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.57 [0.27, 1.21] 1.4e-1 97
15 years 0.00 0.41 [0.18, 0.90] 2.7e-2 38
5 years 0.00 1.14 [0.54, 2.42] 7.4e-1 23
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 1

Survival analyses between endpoints

Plot

before Nontoxic single thyroid nodule
after Nontoxic single thyroid nodule

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic single thyroid nodule

Endpoint not on priority list, no data to show.