Nontoxic diffuse goitre

DOID MESH PheWeb

E4_GOITREDIFF

No definition available.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.0

Hospital discharge: ICD-9 2400

Hospital discharge: ICD-8 240

Cause of death: ICD-10 E04.0

Cause of death: ICD-9 2400

Cause of death: ICD-8 240

2 out of 7 registries used, show all original rules.

865

diagram downward connector

Check minimum number of events None

865

diagram downward connector

Include endpoints None

865

diagram downward connector

diagram downward connector

Remove individuals based on genotype QC

838

diagram downward connector

E4_GOITREDIFF

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E04

Name in latin Struma atoxica diffusa

NAME	E4_GOITREDIFF
CONTROL_EXCLUDE	E4_THYROID
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E040
HD_ICD_9	2400
HD_ICD_8	240
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E040
COD_ICD_9	2400
COD_ICD_8	240
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Nontoxic diffuse goitre based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	838	708	130
Unadjusted prevalence (%)	0.22	0.34	0.08
Mean age at first event (years)	51.02	49.99	56.65

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.67 [0.55, 5.10]	3.7e-1	64
15 years	0.01	1.17 [0.46, 2.98]	7.4e-1	28
5 years	0.00	2.36 [1.09, 5.10]	2.9e-2	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_GOITREDIFF – Nontoxic diffuse goitre
GWS hits: 3

Survival analyses between endpoints

↥

Plot

before Nontoxic diffuse goitre
after Nontoxic diffuse goitre

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Nontoxic diffuse goitre

↥

Endpoint not on priority list, no data to show.