≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Nontoxic multinodular goitre

DOID EFO MESH SNOMED PheWeb

E4_GOITREMULTINOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.2
Hospital discharge: ICD-9 2411
Hospital discharge: ICD-8 241
Cause of death: ICD-10 E04.2
Cause of death: ICD-9 2411
Cause of death: ICD-8 241

2 out of 7 registries used, show all original rules.

6358

diagram downward connector

Check minimum number of events None

6358

diagram downward connector

Include endpoints None

6358

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

6149

diagram downward connector
E4_GOITREMULTINOD

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica multinodularis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 6149 5192 957
Unadjusted prevalence (%) 1.63 2.46 0.58
Mean age at first event (years) 52.50 51.39 58.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.92 [0.63, 1.34] 6.7e-1 495
15 years 0.00 0.68 [0.47, 0.99] 4.2e-2 224
5 years 0.00 1.12 [0.79, 1.58] 5.2e-1 91
1 year 0.00 1.47 [0.88, 2.43] 1.4e-1 21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_GOITREMULTINOD – Nontoxic multinodular goitre
GWS hits: 47

Survival analyses between endpoints

↥

Plot

before Nontoxic multinodular goitre
after Nontoxic multinodular goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic multinodular goitre

↥

Endpoint not on priority list, no data to show.