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Disorders of lipoprotein metabolism and other lipidaemias

DOID MESH PheWeb

E4_LIPOPROT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E78
Cause of death: ICD-10 E78

2 out of 7 registries used, show all original rules.

38658

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Check minimum number of events None

38658

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Include endpoints

38941

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Remove individuals based on genotype QC

37742

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E4_LIPOPROT

Control definitions

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E70-E90
Name in latin Perturbationes metabolismi lipoproteinorum et aliae lipidaemiae

Similar endpoints

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List of similar endpoints to Disorders of lipoprotein metabolism and other lipidaemias based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 37742 16324 21418
Unadjusted prevalence (%) 10.01 7.74 12.88
Mean age at first event (years) 64.48 64.81 64.22

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.82 [2.51, 3.17] 3.4e-67 4920
15 years 0.01 1.47 [1.32, 1.64] 3.9e-12 2133
5 years 0.00 2.98 [2.71, 3.29] <1e-100 1661
1 year 0.00 8.01 [7.12, 9.00] <1e-100 867

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_LIPOPROT – Disorders of lipoprotein metabolism and other lipidaemias
GWS hits: 46

Survival analyses between endpoints

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Plot

before Disorders of lipoprotein metabolism and other lipidaemias
after Disorders of lipoprotein metabolism and other lipidaemias

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Drugs most likely to be purchased after Disorders of lipoprotein metabolism and other lipidaemias

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Endpoint not on priority list, no data to show.