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Type 2 diabetes, strict (exclude DM1)

E4_DM2_STRICT

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not E4_DM1

381686

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC A10B

1 out of 7 registries used, show all original rules.

55561

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Check minimum number of events

Min. number of events 3

55561

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Remove individuals based on genotype QC

57607

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E4_DM2_STRICT

Control definitions

Control conditions not E4_DM1

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 57607 25392 32215
Unadjusted prevalence (%) 15.28 12.05 19.37
Mean age at first event (years) 60.05 58.81 61.03

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: E4_DM2_STRICT – Type 2 diabetes, strict (exclude DM1)
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Type 2 diabetes, strict (exclude DM1)

Endpoint not on priority list, no data to show.