Type 2 diabetes with coma

E4_DM2COMA

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11.00, E11.01, E11.09
Hospital discharge: ICD-9 2502A
Cause of death: ICD-10 E11.00, E11.01, E11.09
Cause of death: ICD-9 2502A

2 out of 7 registries used, show all original rules.

4886

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Check minimum number of events None

4886

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Include endpoints None

4886

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Remove individuals based on genotype QC

4709

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E4_DM2COMA

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 4709 1750 2959
Unadjusted prevalence (%) 1.25 0.83 1.78
Mean age at first event (years) 64.04 62.94 64.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_DM2COMA – Type 2 diabetes with coma
GWS hits: 6

Survival analyses between endpoints

Plot

before Type 2 diabetes with coma
after Type 2 diabetes with coma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 2 diabetes with coma

Endpoint not on priority list, no data to show.