Type 2 diabetes with neurological complications

E4_DM2NEU

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11.4+, E11.4+G59.0, E11.4+G63.2, E11.4+G73.0, E11.4+G99.0

Hospital discharge: ICD-9 2505A

Cause of death: ICD-10 E11.4+, E11.4+G59.0, E11.4+G63.2, E11.4+G73.0, E11.4+G99.0

Cause of death: ICD-9 2505A

2 out of 7 registries used, show all original rules.

1967

Check minimum number of events None

1967

Include endpoints None

1967

Remove individuals based on genotype QC

1894

E4_DM2NEU

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

NAME	E4_DM2NEU
CONTROL_EXCLUDE	E4_DIABETES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E114
HD_ICD_9	2505A
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E114
COD_ICD_9	2505A
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV