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Type 2 diabetes with renal complications

MESH PheWeb

E4_DM2REN

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11.2+, E11.2+N08.39
Hospital discharge: ICD-9 2503A
Cause of death: ICD-10 E11.2+, E11.2+N08.39
Cause of death: ICD-9 2503A

2 out of 7 registries used, show all original rules.

2782

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Check minimum number of events None

2782

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Include endpoints None

2782

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Remove individuals based on genotype QC

2684

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E4_DM2REN

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2684 750 1934
Unadjusted prevalence (%) 0.71 0.36 1.16
Mean age at first event (years) 65.48 64.28 65.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 12.57 [9.14, 17.30] 1.3e-54 994
15 years 0.03 4.56 [3.43, 6.06] 1.6e-25 312
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM2REN – Type 2 diabetes with renal complications
GWS hits: 5

Survival analyses between endpoints

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Plot

before Type 2 diabetes with renal complications
after Type 2 diabetes with renal complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 2 diabetes with renal complications

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Endpoint not on priority list, no data to show.