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Type 2 diabetes

E4_DM2

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11
Cause of death: ICD-10 E11
Medicine purchases: ATC A10B

3 out of 7 registries used, show all original rules.

65307

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Check minimum number of events

Min. number of events 3

65307

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Remove individuals based on genotype QC

63962

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E4_DM2

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 E10-E14

Similar endpoints

List of similar endpoints to Type 2 diabetes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 63962 28212 35750
Unadjusted prevalence (%) 16.96 13.38 21.50
Mean age at first event (years) 58.64 57.31 59.69

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: E4_DM2 – Type 2 diabetes
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Type 2 diabetes

Endpoint not on priority list, no data to show.