Type 2 diabetes with ketoacidosis

E4_DM2KETO

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11.1
Hospital discharge: ICD-9 2501A
Cause of death: ICD-10 E11.1
Cause of death: ICD-9 2501A

2 out of 7 registries used, show all original rules.

676

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Check minimum number of events None

676

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Include endpoints None

676

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Remove individuals based on genotype QC

657

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E4_DM2KETO

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E11

Summary Statistics

Key figures

All Female Male
Number of individuals 657 251 406
Unadjusted prevalence (%) 0.17 0.12 0.24
Mean age at first event (years) 52.76 48.13 55.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_DM2KETO – Type 2 diabetes with ketoacidosis
GWS hits:

Survival analyses between endpoints

Plot

before Type 2 diabetes with ketoacidosis
after Type 2 diabetes with ketoacidosis

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Drugs most likely to be purchased after Type 2 diabetes with ketoacidosis

Endpoint not on priority list, no data to show.