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Alcohol use disorder, ICD-based

PheWeb

AUD

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10.1, F10.2
Hospital discharge: ICD-9 303
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.1, F10.2
Cause of death: ICD-9 303
Cause of death: ICD-8 303

2 out of 7 registries used, show all original rules.

16173

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Check minimum number of events None

16173

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Include endpoints None

16173

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Remove individuals based on genotype QC

15715

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AUD

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 15715 4980 10735
Unadjusted prevalence (%) 4.17 2.36 6.46
Mean age at first event (years) 45.02 41.04 46.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.39 [3.74, 5.16] 1.9e-73 3016
15 years 0.02 2.88 [2.53, 3.26] 4.2e-60 1278
5 years 0.01 4.84 [4.34, 5.40] <1e-100 711
1 year 0.00 14.76 [12.84, 16.97] <1e-100 440

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AUD – Alcohol use disorder, ICD-based
GWS hits: 9

Survival analyses between endpoints

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Plot

before Alcohol use disorder, ICD-based
after Alcohol use disorder, ICD-based

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol use disorder, ICD-based

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Endpoint not on priority list, no data to show.