Other disorders of cornea

H7_CORNEALOTH

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H18
Cause of death: ICD-10 H18

2 out of 7 registries used, show all original rules.

2522

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Check minimum number of events None

2522

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Remove individuals based on genotype QC

2510

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H7_CORNEALOTH

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H15-H22
Name in latin Aliae morbositates corneae

Similar endpoints

List of similar endpoints to Other disorders of cornea based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 2510 1424 1086
Unadjusted prevalence (%) 0.67 0.68 0.65
Mean age at first event (years) 54.40 55.28 53.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.11 [1.28, 3.49] 3.6e-3 185
15 years 0.01 1.26 [0.81, 1.95] 3.0e-1 81
5 years 0.00 2.92 [1.89, 4.52] 1.4e-6 70
1 year 0.00 2.63 [1.37, 5.06] 3.7e-3 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CORNEALOTH – Other disorders of cornea
GWS hits: 7

Survival analyses between endpoints

Plot

before Other disorders of cornea
after Other disorders of cornea

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Drugs most likely to be purchased after Other disorders of cornea

Endpoint not on priority list, no data to show.