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Other disorders of cornea

DOID EFO MESH SNOMED PheWeb

H7_CORNEALOTH

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H18
Cause of death: ICD-10 H18

2 out of 7 registries used, show all original rules.

2522

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Check minimum number of events None

2522

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Include endpoints

2612

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Remove individuals based on genotype QC

2510

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H7_CORNEALOTH

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H15-H22
Name in latin Aliae morbositates corneae

Similar endpoints

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List of similar endpoints to Other disorders of cornea based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2510 1424 1086
Unadjusted prevalence (%) 0.67 0.68 0.65
Mean age at first event (years) 54.40 55.28 53.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.11 [1.28, 3.49] 3.6e-3 185
15 years 0.01 1.26 [0.81, 1.95] 3.0e-1 81
5 years 0.00 2.92 [1.89, 4.52] 1.4e-6 70
1 year 0.00 2.63 [1.37, 5.06] 3.7e-3 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CORNEALOTH – Other disorders of cornea
GWS hits: 7

Survival analyses between endpoints

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Plot

before Other disorders of cornea
after Other disorders of cornea

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other disorders of cornea

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Endpoint not on priority list, no data to show.