Corneal degeneration

DOID MESH PheWeb

H7_CORNEALDYSTROPHY

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H18.4

Hospital discharge: ICD-9 3714

Hospital discharge: ICD-8 37101

Cause of death: ICD-10 H18.4

Cause of death: ICD-9 3714

Cause of death: ICD-8 37101

2 out of 7 registries used, show all original rules.

307

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Check minimum number of events None

307

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Include endpoints None

307

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Remove individuals based on genotype QC

297

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H7_CORNEALDYSTROPHY

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H18

Name in latin Degeneratio corneae

NAME	H7_CORNEALDYSTROPHY
CONTROL_EXCLUDE	H7_SCLERACORNEA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H184
HD_ICD_9	3714
HD_ICD_8	37101
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H184
COD_ICD_9	3714
COD_ICD_8	37101
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Corneal degeneration based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	297	183	114
Unadjusted prevalence (%)	0.08	0.09	0.07
Mean age at first event (years)	60.82	59.64	62.71

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CORNEALDYSTROPHY – Corneal degeneration
GWS hits: 2

Survival analyses between endpoints

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Plot

before Corneal degeneration
after Corneal degeneration

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Table

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Drugs most likely to be purchased after Corneal degeneration

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Endpoint not on priority list, no data to show.