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Other neurological diseases

DOID EFO MESH SNOMED PheWeb

G6_OTHNEU

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G90-G99
Cause of death: ICD-10 G90-G99

2 out of 7 registries used, show all original rules.

8115

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Check minimum number of events None

8115

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Include endpoints

27853

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Remove individuals based on genotype QC

27026

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G6_OTHNEU

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 27026 13455 13571
Unadjusted prevalence (%) 7.17 6.38 8.16
Mean age at first event (years) 60.90 58.40 63.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.77 [2.40, 3.20] 1.5e-43 5119
15 years 0.01 1.54 [1.36, 1.75] 1.7e-11 2144
5 years 0.00 2.96 [2.69, 3.26] <1e-100 1581
1 year 0.00 7.90 [7.02, 8.88] <1e-100 882

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_OTHNEU – Other neurological diseases
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other neurological diseases
after Other neurological diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other neurological diseases

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Endpoint not on priority list, no data to show.