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Other disorders of nervous system

DOID EFO MESH SNOMED PheWeb

G6_NEUROOTH

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G98, G99*
Cause of death: ICD-10 G98, G99*

2 out of 7 registries used, show all original rules.

1809

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Check minimum number of events None

1809

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Include endpoints None

1809

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Remove individuals based on genotype QC

1754

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G6_NEUROOTH

Control definitions

Control exclude G6_OTHNEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1754 863 891
Unadjusted prevalence (%) 0.47 0.41 0.54
Mean age at first event (years) 58.74 56.93 60.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.90 [1.89, 4.47] 1.2e-6 171
15 years 0.01 1.50 [0.99, 2.28] 5.8e-2 76
5 years 0.00 2.95 [1.99, 4.36] 6.5e-8 61
1 year 0.00 4.89 [2.84, 8.41] 9.9e-9 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NEUROOTH – Other disorders of nervous system
GWS hits:

Survival analyses between endpoints

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Plot

before Other disorders of nervous system
after Other disorders of nervous system

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other disorders of nervous system

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Endpoint not on priority list, no data to show.