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Autonomic disorders

DOID EFO MESH SNOMED PheWeb

G6_AUTONOM

autonomic nervous system disease: A disease involving the autonomic nervous system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G90
Cause of death: ICD-10 G90

2 out of 7 registries used, show all original rules.

551

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Check minimum number of events None

551

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Include endpoints

566

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Remove individuals based on genotype QC

549

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G6_AUTONOM

Control definitions

Control exclude G6_OTHNEU

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G90-G99
Name in latin Morbositates systematis nervosi autonomici

Summary Statistics

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Key figures

All Female Male
Number of individuals 549 293 256
Unadjusted prevalence (%) 0.15 0.14 0.15
Mean age at first event (years) 55.08 54.45 55.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.32 [0.66, 8.16] 1.9e-1 78
15 years 0.00 0.68 [0.21, 2.18] 5.2e-1 18
5 years 0.00 4.00 [1.88, 8.52] 3.3e-4 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_AUTONOM – Autonomic disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Autonomic disorders
after Autonomic disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autonomic disorders

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Endpoint not on priority list, no data to show.