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Transient ischemic attack

DOID EFO MESH SNOMED PheWeb

I9_TIA

transient ischemic attack: A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G45
Hospital discharge: ICD-9 435
Hospital discharge: ICD-8 435
Hospital discharge: excluded ICD-10 G45.4
Cause of death: ICD-10 G45
Cause of death: ICD-9 435
Cause of death: ICD-8 435
Cause of death: excluded ICD-10 G45.4

2 out of 7 registries used, show all original rules.

18975

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Check minimum number of events None

18975

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Include endpoints None

18975

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Remove individuals based on genotype QC

18398

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I9_TIA

Control definitions

Control exclude I9_STR_EXH

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Ischaemia cerebri transitoria et syndomata cognata

Summary Statistics

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Key figures

All Female Male
Number of individuals 18398 8636 9762
Unadjusted prevalence (%) 4.88 4.10 5.87
Mean age at first event (years) 65.49 64.68 66.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.30 [1.93, 2.75] 2.9e-20 3841
15 years 0.01 1.39 [1.20, 1.60] 1.1e-5 1721
5 years 0.00 2.58 [2.32, 2.87] 4.9e-68 1244
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_TIA – Transient ischemic attack
GWS hits: 2

Survival analyses between endpoints

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Plot

before Transient ischemic attack
after Transient ischemic attack

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Transient ischemic attack

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Endpoint not on priority list, no data to show.