Cardiomyopathy (excluding other)

FG_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

4269

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Remove individuals based on genotype QC

4156

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FG_CARDMYO

Control definitions

Control exclude FG_OTHHEART

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiomyopathy (excluding other) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 4156 1129 3027
Unadjusted prevalence (%) 1.10 0.54 1.82
Mean age at first event (years) 59.71 57.58 60.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.13 [2.90, 5.88] 3.7e-15 1019
15 years 0.01 2.32 [1.73, 3.11] 2.0e-8 409
5 years 0.01 4.79 [3.81, 6.02] 5.7e-41 294
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_CARDMYO – Cardiomyopathy (excluding other)
GWS hits: 14

Survival analyses between endpoints

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Plot

before Cardiomyopathy (excluding other)
after Cardiomyopathy (excluding other)

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Drugs most likely to be purchased after Cardiomyopathy (excluding other)

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Endpoint not on priority list, no data to show.