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Cardiomyopathy

DOID EFO MESH SNOMED PheWeb

I9_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I42
Cause of death: ICD-10 I42

2 out of 7 registries used, show all original rules.

5710

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Check minimum number of events None

5710

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Include endpoints

6030

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Remove individuals based on genotype QC

5874

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I9_CARDMYO

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I30-I52
Name in latin Cardiomyopathia

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 5874 1931 3943
Unadjusted prevalence (%) 1.56 0.92 2.37
Mean age at first event (years) 59.44 58.05 60.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.17 [3.76, 7.11] 4.4e-24 1335
15 years 0.02 2.60 [1.96, 3.44] 2.5e-11 515
5 years 0.01 5.24 [4.28, 6.41] 4.9e-58 385
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMYO – Cardiomyopathy
GWS hits: 16

Survival analyses between endpoints

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Plot

before Cardiomyopathy
after Cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathy

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Endpoint not on priority list, no data to show.