Cardiomyopathies, Secondary/extrinsic

I9_CARDMSEC

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I42.6, I42.7#
Hospital discharge: ICD-9 4258A
Cause of death: ICD-10 I42.6, I42.7#
Cause of death: ICD-9 4258A

2 out of 7 registries used, show all original rules.

158

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Check minimum number of events None

158

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Include endpoints None

158

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Remove individuals based on genotype QC

156

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I9_CARDMSEC

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 156 50 106
Unadjusted prevalence (%) 0.04 0.02 0.06
Mean age at first event (years) 57.16 52.43 59.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CARDMSEC – Cardiomyopathies, Secondary/extrinsic
GWS hits: 2

Survival analyses between endpoints

Plot

before Cardiomyopathies, Secondary/extrinsic
after Cardiomyopathies, Secondary/extrinsic

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Drugs most likely to be purchased after Cardiomyopathies, Secondary/extrinsic

Endpoint not on priority list, no data to show.