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Unspecified diabetes

DOID EFO MESH SNOMED PheWeb

E4_DMNAS

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E12
Cause of death: ICD-10 E12

2 out of 7 registries used, show all original rules.

74

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Check minimum number of events None

74

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Include endpoints

7721

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Remove individuals based on genotype QC

7455

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E4_DMNAS

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E10-E14
Name in latin Diabetes mellitus malnutritionalis

Similar endpoints

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List of similar endpoints to Unspecified diabetes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 7455 3620 3835
Unadjusted prevalence (%) 1.98 1.72 2.31
Mean age at first event (years) 40.99 37.11 44.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.36 [2.46, 4.58] 2.1e-14 1601
15 years 0.01 1.97 [1.58, 2.47] 2.5e-9 618
5 years 0.00 3.38 [2.84, 4.02] 2.6e-43 344
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNAS – Unspecified diabetes
GWS hits: 19

Survival analyses between endpoints

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Plot

before Unspecified diabetes
after Unspecified diabetes

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetes

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Endpoint not on priority list, no data to show.