Unspecified diabetes with ketoacidosis

E4_DMNASKETO

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E12.1, E13.1, E14.1
Hospital discharge: ICD-9 2501C|2501X
Cause of death: ICD-10 E12.1, E13.1, E14.1
Cause of death: ICD-9 2501C|2501X

2 out of 7 registries used, show all original rules.

271

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Check minimum number of events None

271

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Include endpoints None

271

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Remove individuals based on genotype QC

259

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E4_DMNASKETO

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 259 98 161
Unadjusted prevalence (%) 0.07 0.05 0.10
Mean age at first event (years) 50.01 49.41 50.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_DMNASKETO – Unspecified diabetes with ketoacidosis
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Unspecified diabetes with ketoacidosis

Endpoint not on priority list, no data to show.