Unspecified diabetes without complications

E4_DMNASNOCOMP

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E12.9, E13.9, E14.9
Hospital discharge: ICD-9 2500C|2500X
Cause of death: ICD-10 E12.9, E13.9, E14.9
Cause of death: ICD-9 2500C|2500X

2 out of 7 registries used, show all original rules.

2985

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Check minimum number of events None

2985

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Include endpoints None

2985

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Remove individuals based on genotype QC

2855

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E4_DMNASNOCOMP

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 2855 1185 1670
Unadjusted prevalence (%) 0.76 0.56 1.00
Mean age at first event (years) 54.18 52.50 55.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.98 [4.43, 8.06] 1.3e-31 567
15 years 0.01 2.41 [1.87, 3.09] 5.8e-12 178
5 years 0.01 6.11 [4.88, 7.64] 1.9e-56 177
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_DMNASNOCOMP – Unspecified diabetes without complications
GWS hits: 7

Survival analyses between endpoints

Plot

before Unspecified diabetes without complications
after Unspecified diabetes without complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetes without complications

Endpoint not on priority list, no data to show.