Other diseases of blood and blood-forming organs

D3_BLOODOTHER

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

6877

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D3_BLOODOTHER

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Other diseases of blood and blood-forming organs based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 6877 3891 2986
Unadjusted prevalence (%) 1.82 1.85 1.80
Mean age at first event (years) 56.43 54.26 59.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.55 [3.73, 8.25] 2.3e-17 1151
15 years 0.01 1.96 [1.40, 2.73] 7.8e-5 302
5 years 0.01 6.33 [4.89, 8.18] 5.2e-45 375
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_BLOODOTHER – Other diseases of blood and blood-forming organs
GWS hits: 3

Survival analyses between endpoints

Plot

before Other diseases of blood and blood-forming organs
after Other diseases of blood and blood-forming organs

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Drugs most likely to be purchased after Other diseases of blood and blood-forming organs

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