Other diseases of blood and blood-forming organs

DOID EFO MESH SNOMED PheWeb

D3_OTHERBLOOD

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D75

Cause of death: ICD-10 D75

2 out of 7 registries used, show all original rules.

1835

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Check minimum number of events None

1835

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Include endpoints

D3_FAMIERYTHROCYTOCIS

D3_SCNDPOLYCYTHAEMIA

D3_BLOODNAS

1939

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Remove individuals based on genotype QC

1892

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D3_OTHERBLOOD

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D70-D77

Name in latin Alii morbi sanguinis et organorum haematopoeticorum

NAME	D3_OTHERBLOOD
CONTROL_EXCLUDE	D3_BLOODOTHER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	D3_FAMIERYTHROCYTOCIS\|D3_SCNDPOLYCYTHAEMIA\|D3_BLOODNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D75
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D75
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other diseases of blood and blood-forming organs based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1892	928	964
Unadjusted prevalence (%)	0.50	0.44	0.58
Mean age at first event (years)	57.31	56.19	58.38

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.00 [2.62, 6.11]	1.3e-10	281
15 years	0.01	2.37 [1.59, 3.53]	2.3e-5	136
5 years	0.00	3.34 [2.43, 4.59]	1.2e-13	79
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_OTHERBLOOD – Other diseases of blood and blood-forming organs
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other diseases of blood and blood-forming organs
after Other diseases of blood and blood-forming organs

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Table

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Drugs most likely to be purchased after Other diseases of blood and blood-forming organs

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Endpoint not on priority list, no data to show.