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Functional disorders of polymorphonuclear neutrophils

DOID EFO MESH PheWeb

D3_FUNCPOLYMORPHONUCNEUTRO

obsolete_chronic granulomatous disease: ['A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D71
Hospital discharge: ICD-9 2881
Cause of death: ICD-10 D71
Cause of death: ICD-9 2881

2 out of 7 registries used, show all original rules.

22

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Check minimum number of events None

22

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Include endpoints None

22

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Remove individuals based on genotype QC

21

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D3_FUNCPOLYMORPHONUCNEUTRO

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D70-D77
Name in latin Dysfunctiones granulocytorum neutrophilorum segmentonuclearium

Similar endpoints

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List of similar endpoints to Functional disorders of polymorphonuclear neutrophils based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 21 13 8
Unadjusted prevalence (%) 0.01 0.01 0.00
Mean age at first event (years) 42.32 46.36 35.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_FUNCPOLYMORPHONUCNEUTRO – Functional disorders of polymorphonuclear neutrophils
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Functional disorders of polymorphonuclear neutrophils

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Endpoint not on priority list, no data to show.