Other degenerative diseases of the nervous system

NEURODEGOTH

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G30-G32, G35-G37

Cause of death: ICD-10 G30-G32, G35-G37

2 out of 7 registries used, show all original rules.

13432

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Check minimum number of events None

13432

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Include endpoints

G6_ATROPHCIRCUM

G6_DEGENSEN

G6_DEGENOTH

13575

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Remove individuals based on genotype QC

13086

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NEURODEGOTH

Control definitions

Control exclude NEURODIS

Extra metadata

First used in FinnGen datafreeze DF2

NAME	NEURODEGOTH
CONTROL_EXCLUDE	NEURODIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	G6_ALZHEIMER\|G6_ATROPHCIRCUM\|G6_DEGENSEN\|G6_ALCODEGEN\|G6_DEGENOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G3
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G3
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Other degenerative diseases of the nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	13086	6320	6766
Unadjusted prevalence (%)	3.47	3.00	4.07
Mean age at first event (years)	70.29	66.54	73.79

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: NEURODEGOTH – Other degenerative diseases of the nervous system
GWS hits: 5

Survival analyses between endpoints

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Plot

before Other degenerative diseases of the nervous system
after Other degenerative diseases of the nervous system

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Table

Loading survival analyses table

Drugs most likely to be purchased after Other degenerative diseases of the nervous system

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Endpoint not on priority list, no data to show.